"What is the Mi(gh)ter Hype of Kratom? Pharmacology, Potential Benefits and Harms of Mitragyna speciosa"

Presenter: Oliver Grundman, PhD
Original Date: July 20, 2024

Kratom, a tree native to Southeast Asia also known by its Latin name Mitragyna speciosa, has gained substantial public interest in the US as a botanical product. Its alkaloids act on a number of receptor systems, including opioid, adrenergic, and serotonergic receptors leading to a complex pharmacology. The traditional use in Southeast Asia has not been reported to result in a use disorder although kratom extracts and concentrates sold in the US may lead to tolerance and dependence with frequent and high-dose consumption. This presentation focuses on the pharmacology, reported self-treatment of disorders, and detrimental or toxic effects of kratom.

Bio: Oliver Grundmann is a clinical professor at the College of Pharmacy and holds a courtesy appointment with the College of Nursing, University of Florida. He received his BPharm from the University of Münster, Germany before receiving his PhD in Pharmaceutical Sciences from the University of Florida. His research focuses on natural products and complementary and alternative medicines. He serves as section editor of the journal Current Addiction Reports, is the incoming president-elect of the American College of Clinical Pharmacology, and is working with various academic collaborators on the use and clinical impact of dietary supplements with a particular emphasis on kratom.

NUNM is accredited by the North American Naturopathic Continuing Education Council (NANCEAC). This activity qualifies for 1.5 Pharmacology CEUs.