Proton Pumpaganda
Presenter: Steven Sandberg-Lewis, ND, DHANP
Original Date: January 11, 2026
Did you know that taking a proton pump inhibitor (PPI) plus a statin creates high risk for C. diff diarrhea even in patients who are not taking antibiotics?
Join me for a discussion of all the major risks and benefits of PPIs.
According to a 2023 systemic review of PPI use, clinical guidelines recommend the lowest possible dose for the shortest duration (generally 4–8 weeks). This systematic review observed PPIs being prescribed in higher doses (63.7% of total users) and for longer periods (≥ 1 year: 25.1% of total users). Of long-term users, 65.5% continued for up to 3 years, and 27.8% continued for over three years.
Although generally considered safe for short-term use, evidence of serious side effects with long-term use include increased risk of pneumonia, enteric infection, bone fracture, gastrointestinal tract cancers, and reduced absorption of vitamins and minerals.
Bio: Dr. Steven Sandberg-Lewis has been a practicing naturopathic physician since his graduation from the National University of Natural Medicine (NUNM) in 1978. He has been a clinical supervisor and professor since 1996, specializing in Naturopathic gastroenterology and is licensed to practice in California and Oregon. His private practice is at Hive Mind Medicine in Portland, Oregon (www.hivemindmedicine.org).
Sandberg-Lewis is a popular international lecturer at functional medicine seminars and webinars and is frequently interviewed on issues of digestive health and disease.
His medical textbook is Functional Gastroenterology: Assessing and Addressing the Causes of Functional Digestive Disorders, Second edition, 2017. His newest book, Let’s Be Real About Reflux: Getting to the Heart of Heartburn, is written for both health practitioners and patients. It is a deep dive into underlying mechanisms and natural treatment of gastroesophageal reflux. It is available at functionalgastroenterology.com and all major bookseller websites.
Dr. Sandberg-Lewis lives in Portland, Oregon with his wife, Kayle. His interests include mandolin, guitar and voice; birds and bicycling; writing and lecturing.
NUNM is accredited by the North American Naturopathic Continuing Education Council (NANCEAC). This activity qualifies for 1.5 Pharmacology CEUs Total.