Presenter: Laurie Menk Otto, ND, MPH

Original Date: June 4, 2017

SIBO is a functional bowel disorder that remains controversial from a diagnostic perspective. The invasiveness of gold-standard diagnostic methods creates a need to develop alternative diagnostic methods that are accurate. Over the past 2 years, the National University of Natural Medicine has been conducting a clinical case-control study to investigate differential biomarker patterns for SIBO that improve diagnostic sensitivity. Specifically, physician-diagnosed SIBO cases (target n=50) and asymptomatic controls (target n=50) were tested for breath hydrogen and methane per manufacturer testing recommendations, and results were compared between groups. Additional biomarkers of gut inflammation, food intolerances via IgG testing, autoimmune cross-reactivity via IgG testing and microbiome differences were measured and compared between groups. Factor analyses will be performed in order to determine if more than 2 distinct testing patterns are apparent. Initial lessons from breath testing, including internal estimates of sensitivity and specificity are shared in this presentation.

0.75 General CEUs approved by OBNM

0.75 Category B credits approved by the California Board of Chiropractic Examiners