Presenter: Mark Pimentel, MD

Original Date: June 3, 2017

The mechanisms for SIBO are more complex in 2017. There is now evidence that food poisoning is a cause of SIBO and that most of IBS is SIBO. The way food poisoning may be contributing to SIBO is through the development of autoimmunity. In this lecture, the development and measurement of autoimmunity in these subjects are described.

In addition, methane is unique in SIBO in that it contributes to constipation. Methane gas itself slows transit in the gut. By manipulating methane, constipation can be improved. Interestingly, methane is produced by an organism called M. smithii. This organism has unique properties and new treatments are being developed to help patients based on these. In this lecture, we discuss some pharmaceuticals including rifaximin, neomycin, and lovastatin.

0.5 Pharmacology and 1.0 General (Total 1.5 CEUs) approved by OBNM

1.0 Category B credits approved by the California Board of Chiropractic Examiners