Presenter: Mark Pimentel, MD

Original Date: March 16, 2019

SIBO is a common condition and with great overlap between SIBO and IBS. In fact, SIBO may be the cause of IBS in up to 70% of cases. We also know that food poisoning (acute gastroenteritis) can be a trigger for IBS/SIBO but the mechanisms for this have been unknown. Recent data suggest that food poisoning creates an autoantibody that can cause IBS and SIBO based on animal and human studies.

This presentation explores the data around how autoimmunity is triggered after food poisoning and in the development of IBS and SIBO. We will also explore how this could change the prognosis of IBS and SIBO.

Pharmaceutical agents discussed include rifaximin and neomycin. There is also discussion of prokinetics such as prucalopride and erythromycin.

0.5 Pharmacology and 1.0 General (Total 1.5 CEUs) approved by OBNM